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Preventing blindness in children – genetically modified rice to naturally grown sweet potatoes



New Scientist (18 August 2012) reports that Golden Rice can prevent blindness. It contains a precursor to vitamin A deficiency which blinds an estimated half a million children each year, particularly in undeveloped countries. The problem is that it is genetically modified, and therefore there are many opponents to its use.

There is another alternative. A sweet potato, grown naturally in Uganda, contains a lot more beta carotene than other sweet potatoes. Beta carotene helps stave off vitamin A deficiency because it is converted into vitamin A in the body.

About half a million children in Africa and Asia suffer blindness every year due to the lack of vitamin A in their diet, which is vital for vision and the immune system. Of those who lose their sight, 66% die within months.

Aid agencies currently treat vitamin A deficiency with high-dose vitamin A capsules administered twice a year. However, eating locally grown food rich in the vitamin would be more practical and sustainable. The orange flesh of a new strain of sweet potato in Uganda has four to six times more beta carotene than other sweet potatoes. A two-year project (by the International Food Policy Research Institute in Washington DC, America) involving 10,000 households in Uganda found that vitamin A intake doubled in women and children (aged 6 months to 3 years) who ate the new strain of sweet potatoes, compared with families that ate the regular varieties. By the end of the project almost 90% of the children eating the new strain had prevented vitamin A deficiency, compared with 50% in the control group (eating other varieties).

Growing the new strain of sweet potato in Uganda is not controversial because it is grown naturally and locally. However, the solution for Uganda may not necessarily be a solution everywhere. Some say that as many different options as possible are required to prevent blindness in children around the world.

There is another solution, but it is genetically modified rice called Golden Rice. Golden Rice is genetically engineered to contain 30 micrograms of beta carotene per gram. Ordinary rice has no beta carotene. Critics claim that rice is impractical as people would need to eat huge amounts (as much as 18 kilograms of cooked rice a day) to obtain enough vitamin A.

A study involving 68 Chinese children refutes the criticism. Scientists from the University of Boston in Massachusetts, America, have demonstrated that just 100 to 150 grams of the genetically modified (GM) rice (about half of the children’s daily intake) would provide 60% of the recommended daily intake of vitamin A. The children were given beta carotene in the rice, in pure form in oil, or in spinach (distinguished from the vitamin A already circulating in their blood). Analyses showed that it took 2.3 grams of beta carotene derived from rice to make a single gram of vitamin A – only marginally less efficient than the 2 grams of beta carotene derived from the oil given to students. Therefore, Golden Rice has the potential to be used widely, despite objections, to counteract blindness in children.

Opponents to the Golden Rice argue that there are other options. Proponents say that to address the problem of child blindness, and potential death, as many options as possible should be considered. They say that the success of the sweet potato grown in Uganda shouldn’t mean that GM foods should be definitively or permanently discounted. Other options may take time, which then places vulnerable children more at risk. They acknowledge that commercial GM food is risky business but suggest that, as rice is commonly grown locally in many regions of the world, GM Golden Rice may help an estimated half a million children a year from blindness and two-thirds of them from death.  



(www.newscientist.com)

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